What You Will Learn About 1P LSD
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- 1P LSD is a psychedelic substance of the lysergamide class and is considered an analogue of LSD and homologue of ALD-52. It also could be a “prodrug” of LSD.
- The legality of 1P LSD varies from country to country. However, it is illegal in 13 countries.
- Because it is so closely related to LSD, it is considered relatively safe to use. However, there are increased risks if you have a pre-existing medical condition, heart condition, or are on certain kinds of medications.
- 1P LSD first appeared online in 2015 as a designer drug. We don’t know who first created it, although some speculate that it was Alexander Shulgin.
What is 1P LSD?
1P LSD is short for 1-propionyl-lysergic acid diethylamide. As an analogue of LSD and homologue of ALD-52, it is classified as a psychedelic substance of the lysergamide class. 1P LSD is made by adding a propionyl group to the nitrogen molecule of LSD’s indole. In other words, it is the same substance as LSD with an additional chemical chain. Recently, it has become available as a research chemical in the form of blotters and powdered material. Typically, it takes 45-90 minutes to begin to feel the effects and lasts anywhere between 8-12 hours. 1p lsd for sale
Though 1P LSD functions similarly to LSD, too little research exists to make definitive claims. However, due to its chemical similarities, it functions as a serotonergic substance. It binds to the 5-HT serotonin receptors in the brain or body. The way LSD binds to the 5-HT2A receptor, in particular, causes a cross-activation of the 5-HT2A receptor heteromer. In other words, this relationship produces long-lasting psychedelic effects. 1P-LSD probably binds with the monoamine receptors responsible for dopamine and norepinephrine but, again, little data exists to back up these claims.
A study from 2015 indicated that 1P-LSD shows 38% the potency of LSD in mice, though the drug did exhibit LSD-like behavior. There is a theory that 1P-LSD may act as a prodrug for LSD, which would mean that it turns into LSD once metabolized in the body. However, more studies need to be conducted in order to determine how 1P-LSD functions and if it is capable of producing its own psychedelic effects.
1P LSD vs LSD: What’s the Difference?
Subjectively speaking, users claim that the effects are more or less identical. However, a recent study investigated the similarities and differences in mice. Researchers found that 1P LSD shows 38% of the potency of LSD. This could indicate that 1P LSD is a prodrug, which means that it metabolizes into LSD in the body. The process could make 1P LSD weaker in comparison as well as slower to take effect. According to users, however, this does not seem to accurately reflect their experiences.